There's a new antibiotic which can be made specifically for each gram-negative bacteria. Due to it being so selective, the impact of making other bactiera resistant is no longer an issue. Additionally, we've got to get back to studying bacteria phages in detail. These are viruses which only attack bacteria and they evolve faster than bacteria. But phages were written off after the discovery of penicillin. These numbers are scary, but thankfully there's many intelligent folks working to prevent this from happening!

Looks like trolCommander, muCommander, and WinSCP all have FTP support on Windows.

There's a few of them, the open source options include Double Commander, Files, Explorer++, Spacedrive (links files from multiple devices into one explorer), and Sigma File Manager. QTTabBar is an extension for the windows file manager which provides tabbed browsing as well. Here's a list covering these and many others with links to official websites for each one: https://alternativeto.net/software/windows-explorer/?p=2

On top of that, in the 2010 massive Cholera outbreak, there's images of UN sewage trucks dumping waste into the local water ways. While it was responsible for an obscene initial death toll, the country still has this Cholera strain actively being spread, confirmed via genetic analysis. In a country with fragile water filtration infrastructure, a severe lack of vaccinations, and a heavy distrust in the local government, this was a perfect storm which the repercussions are still being felt to this day... Stay away from Haiti UN, you've already done enough!

Take a bigbig middle finger and hopefully it'll break your soul unlike the thousands prior. Seriously, WTF, new cop out just dropped!!! lol

It's a University of California, the fact the article focuses on the US constitution doesn't void the state's constitution. Both federal and state governments have authority here. Maybe think outside the box whatever you're reading is painted in? It's without question a good practice.

Are they not people? People are referenced numerous times throughout the US constitution. Additionally, this is a state run institution, so the California constitution is also applicable. California's constitution explicitly covers rights and protections for students as well as faculty. Students have protection for speech and it prohibits disciplining students for this protected speech. Maybe think a bit longer before hitting post, it would help to prevent you coming across as a narcissistic imbecile...

Yep, Millennials were born between 1981 and 1996.

Ever pop your ears when going up a mountain or during flight? This is air pressure changes. Either way, water tight does not mean air tight, while air tight does mean water tight assuming the material is not water soluble.

It's ludicrous everyone understands biology operates on spectrums. Brown eyes, yep, large range of eye coloration are "brown". White skin, yep, large array of skin tones are "white". Even like the flavor of tomatoes, yep, vast differences. Genetic variation within a population is what keeps a species viable. Yet when it comes to the genetic makeup and expression of sex chromosome linked traits, fuck you, it'd without question this or that...

Cases for West Nile Virus (WNV) typically peak around mid- to late-September, based on the 3 year rolling average from 2021 - 2023 in NY. The median for cases reported in the US each year is 2,205, with a range of 712 - 9,862. It has a mortality rate for people with severe illness of 3 - 15%. But 1 in 150 (0.6%) infections result in encephalitis or meningitis, which are considered server illness. So, unless you're elderly, you'll almost certainly just be under the weather.

There's definitely an upward trend of arboviruses in the northern hemisphere, but they tend to be more common in Europe than America currently. Nonetheless, if you truly feel like you have WNV, it's ALWAYS better to get treatment sooner rather than later. While there's no specific WNV treatment, they can assess the severity, provide some relief, and put up restrictions to help stop the spread!

I dig https://perplexity.ai as it doesn't require an account, it provides sources for the answers given, and it has filters such as academic, math, writing, and web. They've been in hot water recently for scrapping websites which prohibit scrapping, but that can be seen as a good or bad thing depending on your viewpoint.

While not every coin is decentralized as referenced above, you know it all inside and out. Especially since "gear heads" are definitely the only people capable of using a USB drive and keeping software up to date for cold storage.

You understand there's over 13,000 cryptocurrencies, right? Your broad statement here is no different from stereotyping someone based on physical appearance. How many whitepapers, aka detailed business plans for coins, have you read? There are always scammers online, in every industry, across the board. But while there are many bullshit coins, there's still unquestionably very solid options.

For example, BTC has no website, no office, no owner, and is fully decentralized. Other examples of decentralized coins include ETH, XMR, ZEC, LINK, DAI, GRT, AAVE, INJ, and MKR to name a few. It's a great practice to research and analyze data before making a statement on topics you're unfamiliar with, but to each their own.

Couldn't agree more, I don't even see the benefit here for Binance at all, this will be horrible for their PR. Especially since most crypto investors view cryptocurrency as a way to circumnavigate government financial control and the associated inflation. Regardless if you love or hate crypto, FUCK Binance through and through!

One huge component to natural selection is the limited availability of resources. The preference for quite specific environments is partially due to a lack of other organisms being able to thrive in it. But you seem to know fungi well, are you a mycologist?

Ya, they should have worded the title more accurately. It's a reference to your biological age, which is the age of your cells/tissues/organs. You have a variation of biological ages across your different cells/tissues/organs. This makes it pretty wild the education of your grandparents would have any impact on it!

Well, tolerance is a pretty wild construct. For some substances it's physical, with others it's mental, and some are a mix of the two. I know with alcohol, it's primarily a mental tolerance. This why some folks blow something insane like a 0.2 BAC. I believe with weed it's more a combo, but when you smoke different strains, it highlights different subserotonin receptors. This is basically natures natural loop hole in mental tolerance. As you change up what specific neurons are being activated, based on the terpene profile in the herb, it works around tolerence while also changing up the experience. So no need to research it more than that I'd think, right?

I'd recommend https://privatebin.info, https://toptal.com/developers/hastebin, or https://rentry.co. All are open source and awesome replacement options. PrivateBin is a software package you download, while the other two are webapps.

Yep, the part you highlighted there is super spot on. Crazy to see the various fashions tech corps will implement to become embedded in governments. But seems as if China's approach is more reasonable than the US approach.

That'll make it so you're not bothered by banners anymore, so I'd say yes. I activate everything listed and then import others filters from filterlists.com. Here's a link which will let you add the Easylist Cookie Lists: https://filterlists.com/lists/easylist-cookie-list

I'd recommended adding EFF's Cookie Block List, which you can find here: https://filterlists.com/lists/eff-cookie-blocklist

uBlock doesn't block cookies directly but it can be setup to block the domains associated with cookies. Adding the EasyList Cookie will accomplish this. It will prevent websites from setting cookies when you visit them. As far as essential cookies go, I'd assume the Easylist blocks cookies which won't affect the websites function.

That's bonkers, you do know how much money Google makes off selling data and ads, right? Being able to track folks physical location and a majority of their internet activity is a big piece of their advertising revenue. Google makes most of their revenue from ads and user data, no longer developing Android would be idiotic, this being the case.

What about the MullVad browser? I'm really liking it so far, been using it as my daily driver for a bit now, it's rad!

The fuck!? I'm already late for work, I don't have time to Finish Him, or anyone! I got to get to the office!!

It's 100% a feature! Truly a horrendous approach to lock down a device someone purchased to the extent seen on Windows.

Linux can't prevent you from permanently removing files. While in Windows it's a chore to remove a number of files/bloat, which are then most often back after a system update.

Yep, @gravitas_deficiency@sh.itjust.works knows what's up. PFAS are one group of forever chemicals. While 2,3,7,8-tetrachlorodibenzofuran (TCDF) shares many characteristics with “forever chemicals” like PFAS, including persistence, bioaccumulation, and toxicity, it belongs to a different chemical class (Persistent Organic Pollutants aka POPs). Nonetheless, its environmental and health impacts are significant, and efforts are needed to reduce its presence in the environment!

This is another reason to favor Beyond over Impossible! Additionally, Beyond has always been gluten-free while Impossible made their recipe gluten-free years down the road.

In part, according to one of the head researchers, “compared to prior studies that relied solely on epidemiological data, we integrated multiple layers of information, including epidemiological data, conventional metabolic biomarkers, and cutting-edge metabolomics”.

So in addition to finding the metadata, they also dug into the biomarkers present, which the molecular pathways are already known in detail. On top of this, metabolomics interpreted the chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Together, these aspects helped demonstrate the molecular consequences of ingesting animal products. The epidemiological layer assessed the incidence rate of developing T2D and then investigated how many involved the consumption of animal products for the individuals.

This being the case, it appears to be more than just correlation, as once the metadata was found, the team investigated the causation of the metadata's findings.

This is wild, TLR4 is associated with our immune system's identification of LPS, which is found in the outer layer of gram-negative bacterial cells. So why it's associated with the SARS-CoV-2 virus is mind-bending. For anyone interested in the TLR's found in the immune system, here you go:

It's well-known NF-kB is directly associated with NOD-Like-Receptors, which produces inflammation as an inflammasome. This is what allows immune cells to target the area in numbers. But the TLR4 involvement here is puzzling, would have 100% bet against its involvement in the immune response to SARS-CoV-2!

Edit: For clarity, S100 proteins are only found in vertebrates, and Heparan Sulfate is expressed by mammals on cell surfaces and in the surrounding extracellular matrix. HMGB1 works as a chromatin binding factor in our bodies. HSP60 + HSP70 (known as Heat Shock Proteins) are found in both prokaryotes and eukaryotes and are a response to stressful conditions. They're basically chaperones and help control protein folding, transport, degradation, cell differentiation, and translocation. But viruses aren't prokaryotes, so the HSPs they're using during an infection are from the host. This helps show why I'm soo blown away with TLR4 being involved here!!

I went with Petlibro for the feeder and fountain, they've worked well for me.

I bought my cat an auto feeder and a filtered water fountain. Definitely quite pricey, but it's amazing not getting woken up by meows to feed her each morning. Plus, it keeps her on a consistent schedule and seems like she drinks much more water with the filtered fountain too.

K-9 Mail is my go to as well. It was bought by Mozilla a little while back to be the mobile app for Thunderbird. Still waiting on it to be fully integrated as a mobile Thunderbird app, but it's nice knowing all the data is handled by Mozilla until then at least.

Arnold H. Glasow basically covered this indirectly when he said "the fewer the facts, the stronger the opinion."

All three are in my rotation. But I spent time in Firefox's about:config to remove all the Google BS and some other aspects which can be used in tracking.

What I never see covered is how Project 2025 is built off of the Mandate for Leadership published in 1981, which was associated with Ronald Reagan. There was also one published in 2015 when Trump ran for the first time. Project 2025 is basically an updated version of the 1981 and 2015 publications. Granted, it's atrocious, but it's all been referenced in some fashion before. This makes the intense focus on Project 2025 seem a bit odd, especially when I don't remember it being discussed at all in 2015.

I studied Microbiology and Immunology in undergrad and now working on an immunology PhD. It's for sure my favorite system to study. Check out Jane Way's Immuno Biology. It's an amazing book to get comfortable with how elaborate the immune system function is in our bodies. Learning something new everyday is a goal of mine, sounds like it's the same for you too, which is fun. But ya, immunology is the bee's knees's!!!

Ya, feedback loops are everywhere in the body. It's basically the default for any reaction involving enzymes, which is most of them. But since heart attacks are a clogging of the passage and only result in tissue damage, I could only see this being used afterwards. But with spinal injuries, it maybe a different story.

I'd bet the collagen is there to ensure it's well received in the heart. As collagen is the main structural protein in the extracellular matrix of a body's various connective tissues. It could also be a guide to ensure it goes to the right location.

Well, it's definitely not an antagonist, it's more the activator of healing if anything. When used for spinal cords, it was "injected as a liquid, the therapy immediately gels into a complex network of nanofibers that mimic the extracellular matrix of the spinal cord. By matching the matrix’s structure, mimicking the motion of biological molecules and incorporating signals for receptors, the synthetic materials are able to communicate with cells." So the motion is just used to active the tissue repair process.

When it comes to immune cells, Th2 is only found as the primary immune pathway in the heart after cardiac arrest. Beforehand it's mainly Th1, which is ideal to eliminate forien bacteria as well as viruses. Th2 is primarily for parasite defense, while also resulting in allergies and the regeneration of mucus. This is a contributing factor in being more likely to have a 2nd cardiac arrest after the 1st.

Th2 vs Th1 is a complex relationship, and it's primarily formed earlier in life. This is why some folks in the 70s used tape worms to cure aliments. It shifted the Th1 response to Th2, providing some relief, yet you had a tape worm in you...