A monument to one of the most famous cases in medicine and psychology - that of Phineas Gage - is in Cavendish, VT near the site of Gage's injury

If you are not familiar with the case, you can read more on Wiki.

TL;DR Phineas Gage had a big iron rod travel through his brain in an explosion in 1848. He survived but suffered significant personality changes. This became the topic of great debate about the brain and its functions.