List of URL parameters · omarroth/invidious Wiki · GitHub

Append & and the parameter to any Invidious URL to use them.

The one I use the most is listen=true or the shorter version listen=1 to play only the audio.

Also, use the preferences (and allow cookies for the instance) if you want to make any of these changes permanent. I overlooked the configuration button for a long time.

Edit: linking search operators which is also useful. More interesting things in the wiki.