Redefining Dementia Treatment: Berkeley Scientists Unveil Promising New Breakthrough

This research indicates that in neurodegenerative conditions ongoing stress caused by protein aggregation is leading to the death of brain cells. This reports a ubiquitin-dependent mechanism that silences the cellular response to stress. Stress response silencing was found to sustain cell survival even if stress resolution failed.

https://www.nature.com/articles/s41586-023-06985-7 (open access)